Author: Brian

The Department of Medicine, in an effort to support the professional development of women within the department, sponsored several faculty and trainees to attend virtual conferences, including the WIMSummit, September, 2021 and the Harvard Medical School Career Advancement and Leadership Skills for Women in Healthcare conference, November, 2021. Both conferences delivered a variety of professional […]

Recognized for commitment to medical education, training residents

Method, in mice, can eliminate need for chemotherapy, radiation, in treating blood cancers, other diseases

Karen Joynt Maddox’s career as a health policy researcher sparked from an initial interest to affect change in the world around her. Today, Joynt Maddox, MD, MPH, associate professor with the Cardiovascular Division and Co-Director of the Center for Health Economics and Policy at the Institute for Public Health at Washington University, is doing just […]

Study suggests older drug may be safer for an advanced form of heart failure

Many inflammatory disorders are linked to an overactive NLRP3 inflammasome due to increased cell death and production of inflammatory cytokines.  In some cases, targeting the pyroptosis (an inflammatory form of cell death) pore forming unit GSDMD alleviates these disorders, but the direct role of GSDMD during sustained NLRP3 inflammasome activation is unclear. Using various knockout […]

Grant funds development of ‘living factories’ to produce antibodies, anti-nerve agents

Eight researchers at Washington University in St. Louis have received funding from the Longer Life Foundation, a cooperative effort between Washington University School of Medicine and the Reinsurance Group of America.

Sponsored by the Academy of Educators, the School of Medicine’s Education Day was held on Tuesday, October 5, 2021. The event featured a variety of educational topics, a celebration of new inductees to the Academy of Educators and education-focused award recipients, followed by a networking session to wrap up the day. Education Day is held […]

A cross-discipline team of School of Medicine and Department of Medicine researchers have published, “Breast cancer-derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment” in The Journal of Clinical Investigation.  The team of researchers found that breast cancer cells secrete lactic acid and a signaling protein, GM-CSF. GM-CSF in the acidic […]

Elusive senescent cells are subject of new national research consortium

Findings could lead to better therapies for respiratory syncytial virus infection

Available, FDA-approved drugs may be effective in targeting about 80% of never-smokers’ lung tumors

Will study how chikungunya virus causes chronic disease

This episode of ‘Show Me the Science’ highlights how stay-at-home orders changed the initial trajectory of the pandemic

Delays in implementing public health orders likely would have resulted in many more hospitalizations, deaths

In mouse study, rewired cells automatically release biologic drug in response to inflammation

Attention to kidneys important part of post-COVID-19 care

However, people treated for autoimmune conditions produce weaker responses than healthy people

Study points to mechanism of post-viral lung damage; suggests targets of intervention

Could form basis of universal therapy, vaccines for alphaviruses

Research program investigates link between viral infections, memory problems

$8.8 million to fund research into interaction of specific genes with demographic, lifestyle factors

Smartphone system complements traditional contact tracing

Bone and mineral disease specialist will serve 5 years in post

The CTSA program was developed to accelerate new treatments from the lab to patients, enabled to a large extent by patients participating in and benefiting from clinical trials. Clinical trials provide that needed bridge from human subjects to hypotheses to treatments that can directly benefit human health. And, never has this connection been more critical […]

This episode of ‘Show Me the Science’ looks at how doctors have tried to protect themselves, their babies and their patients during the pandemic.

Many people, including me, have experienced a sense of gratitude and relief after receiving the new COVID-19 mRNA vaccines. But all of us are also wondering how long the vaccines will remain protective against SARS-CoV-2, the coronavirus responsible for COVID-19.

Sales of antibiotics soar as threat of drug-resistant bacteria worsens

Effective against blood cancers, natural killer cells also may be effective against solid tumors

Vaccines likely induce strong, persistent immunity to COVID-19

Retrospective study also indicates outcomes of critically ill patients in ICU improve when given antibodies from recovered COVID-19 patients

Program supports doctors who want to conduct basic science research

Targeted therapy shrank tumors, shows promise in improving survival

Nanofiber device allows insulin to be released while defending against immune cells

Such data now available to university researchers, could help speed research

Physician-scientist was a pioneer in mass spectrometry research