Identifying how the body regulates fat breakdown during metabolic stress

Irfan Lodhi, PhD, Professor of Medicine in the Division of Endocrinology, Metabolism & Lipid Research at WashU Medicine, and collaborators are authors of a study published January 8, 2026, in Nature Metabolism. The article, titled “A catecholamine-independent pathway controlling adaptive adipocyte lipolysis,” investigates how the body breaks down stable fat stores during conditions such as starvation, wasting and cachexia.