Category: The DOM Insider

Each colored stripe in the image above represents a unique virus particle, with the width of each stripe reflecting the number of copies, in a hamster infected with SARS-CoV-2, the virus that causes COVID-19. Jacco Boon, PhD, a professor of medicine in the Division of Infectious Diseases, and colleagues have developed a tool to study […]

Brian Gage, MD, MSc, Professor of Medicine in the Division of General Medicine & Geriatrics, research on mycophenolic acid in lung transplant recipients has been published in the Journal of Heart and Lung Transplantation.

The first study to assess how weight-loss drugs affect the whole of human health has discovered an “eye-opening” impact on the body, researchers say.

Researchers are working with industry toward a clinical trial for blood cancer patients Two new studies led by researchers at Washington University School of Medicine in St. Louis have identified a possible way to block the progression of several forms of blood cancer using a drug already in clinical trials against breast cancer.

Off-the-shelf CAR-natural killer cells could expand accessibility, reduce cost of cell-based cancer therapies

Jeffrey P. Henderson, MD, PhD, FIDSA, Professor of Medicine and Molecular Microbiology, at WashU Division of Infectious Diseases, was recently published in ASM Journals with new insights into the development of a metabolome-based respiratory infection prognostic during COVID-19. Henderson highlights that the supportive environment at WashU Medicine played a crucial role in making this work possible, […]

In March, Samantha Adamson, MD, PhD; Sangeeta Adak, PhD; Max C. Petersen, MD, PhD; Dustin Higgins, DO; Larry D. Spears, PhD; Rong Mei Zhang, MD; Andrea Cedeno, MD; Alexis McKee, MD, CDCES; Aswathi Kumar, MD; Sudhir M. Singh, MD;  Fong-Fu Hsu, PhD; Janet B. McGill, MD, MA, FACP; and Clay F. Semenkovich, MD had their article titled “Decreased sarcoplasmic reticulum phospholipids in human skeletal muscle are associated with metabolic […]

The brightest minds solving brain cancer’s toughest challenges. Brain tumors are among the most challenging cancers to effectively treat. Depending on the tumor’s location, surgery can interfere with cognitive function, movement or language, and surgery often is not the solution because the tumor cells are invasive and intertwined with normal brain cells. Additionally, the brain’s […]

Clinical trial indicates safety, fewer cases of life-threatening graft-versus-host disease than expected Adding a new drug to standard care for stem cell transplant recipients may reduce a life-threatening side effect, according to an early-stage clinical trial conducted at Washington University School of Medicine in St. Louis. The trial showed that patients being treated for various […]

A small clinical trial shows promising results for patients with triple-negative breast cancer who received an investigational vaccine designed to prevent recurrence of tumors. Conducted at Washington University School of Medicine in St. Louis with a therapy designed by Washington University researchers, the trial is the first to report results for this type of vaccine — known […]

A polypill is suggested containing all 4 classes of guideline-directed medical therapy for heart failure Justin Chen, MD, First Year Cardiology Fellow, First Author along with Anubha Agarwal, MD, MSc, Assistant Professor of Medicine, Co-Director, Program in Global Cardiovascular Health, WashU Medicine Cardiovascular Division, Senior Author, have published in Circulation: Cardiovascular Quality and Outcomes. The […]

A new analysis led by researchers at Washington University School of Medicine in St. Louis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells — and the cells of a tumor’s surrounding environment — are organized, in 3D, and how that organization changes […]

The Center for Dissemination and Implementation announces the launch of a new Midwest Developmental Center for AIDS Research (D-CFAR) in Missouri, which brings together researchers from across the translational spectrum to address the HIV epidemic. This D-CFAR is part of a national network of 20 NIH-funded centers, and it is the first of its kind […]

A new research network initiative is being launched by Sunny Lin, PhD, MS, in the Division of General Medicine & Geriatrics – Research Unit.

Gewin’s team aims to find ways to promote kidney repair and prevent the progression of fibrosis. Dr. Leslie Gewin, a nephrologist and researcher, has been steadily expanding her research into kidney disease since moving from Vanderbilt to WashU Medicine three years ago. Leveraging the university’s extensive resources and collaborative environment, Gewin’s work focuses on the […]

A new study from Washington University School of Medicine in St. Louis suggests that a type of immunotherapy — similar to that approved by the Food and Drug Administration (FDA) to treat inflammatory conditions such as arthritis — also may be an effective treatment strategy for heart failure.