Nasal vaccine combats bird flu infection in rodents (Links to an external site)

Researchers at WashU Medicine have developed a nasal vaccine against the highly pathogenic H5N1 avian influenza virus, or bird flu, which has jumped from wild birds to livestock to humans. When tested in rodents, the vaccine elicited a strong immune response and prevented infections in animals exposed to H5N1.

Since it was first detected in the U.S. in 2014, H5N1 avian influenza, commonly known as bird flu, has jumped from wild birds to farm animals and then to people, causing more than 70 human cases in the U.S. since 2022, including two fatalities. The virus continues to circulate among animals, giving it the opportunity […]

Hospitalists take next steps to Implement Diagnostic Accuracy Improvements (Links to an external site)

Radha Devi, MD, Timothy Evans, MD, and Rob Young, MD

Radha Devi, MD, Timothy Evans, MD, and Rob Young, MD, have been spearheading the ADEPT (Achieving Diagnostic Excellence Through Prevention and Teamwork) initiative at WashU in collaboration with Colorado’s Institute for Healthcare Quality, Safety, and Efficiency (IHQSE). Along with 14 other academic medical institutions across the United States, the WashU ADEPT team is leading the […]

Transforming global heart health: The polypill strategy (Links to an external site)

Anubha Agarwal, MD, MSc

Cardiovascular disease (CVD) is the leading cause of death and disability worldwide. These conditions, which include atherosclerosis, heart attack, stroke, and heart failure, cause one in three deaths globally and one in five in the United States. Beyond that stark reality, those living with the conditions may contend with disability, psychological distress, financial burden, and […]

Trautner contributes to IDSA Clinical Guidelines for cUTIs

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Complicated Urinary Tract Infections (cUTI): Clinical Guidelines for Treatment and Management IDSA has released the first IDSA guidelines on management and treatment of complicated urinary tract infections (cUTIs). These guidelines provide practical advice for clinicians who manage patients with cUTIs in inpatient and outpatient settings. Barbara Trautner, MD, PhD, Co-Chief, WashU Medicine Division of Infectious […]

Millman’s technology succeeds in new stem cell therapy trial, offering hope for type 1 diabetes (Links to an external site)

Jeffrey R. Millman, PhD

A groundbreaking clinical trial utilizing technology developed previously by Jeffrey R. Millman, PhD has reported promising new findings in the treatment of type 1 diabetes (T1D). The study, conducted by Vertex Pharmaceuticals, evaluated a stem cell-derived islet (SC-islet) replacement therapy known as Zimislecel. In this Phase 1/2 trial, researchers implanted SC-islets into patients with T1D to replace the […]

2025 Castle Connolly Top Doctors®

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The Department of Medicine is proud to announce that 168 of our faculty have been selected for the 2025 Castle Connolly Top Doctors® list. The Top Doctors® selection process is entirely merit-based. Doctors cannot pay to be listed. These doctors are best-in-class healthcare providers, embodying excellence in clinical care as well as interpersonal skills. More […]

Environmental hygiene intervention burden in hospital sinks: a prospective study

Kwon

The effects of a prospective sink environmental hygiene intervention on Pseudomonas aeruginosa and Stenotrophomonas maltophilia burden in hospital sinks Jennie Kwon, DO, MSCI, Associate Professor of Medicine at WashU Medicine’s Division of Infectious Diseases, co-published research in eBioMedicine about the burden of hygiene in hospital sinks. Co-principal investigators are; Gautam Dantas, PhD, Conan Professor of Laboratory and Genomic Medicine, and […]

Advanced Heart Valve Procedures Expand Treatments for Patients With Limited Options (Links to an external site)

transcatheter tricuspid valve replacement (TTVR) and transcatheter edge-to-edge repair (T-TEER) procedures for tricuspid regurgitation treatment

With the U.S. Food and Drug Administration (FDA) approval of transcatheter tricuspid valve replacement (TTVR) and transcatheter edge-to-edge repair (T-TEER) procedures for tricuspid regurgitation treatment, heart specialists at the Washington University and Barnes-Jewish Heart & Vascular Center in St. Louis, Mo., are pioneering advances that enhance the quality of life for patients who have historically suffered debilitating […]

Nigeria Launches Sodium Reduction Guidelines Developed with WashU Medicine Research (Links to an external site)

Mark Huffman, MD

Research developed through the collaborative efforts of WashU Medicine, the University of Abuja, Northwestern University, and The George Institute for Global Health have supported the launch of Nigeria’s Sodium Reduction Guidelines. William Bowen Endowed Professor of Medicine and Global Health Center Co-Director Mark Huffman, MD, MPH headed the WashU team for this NIH-funded project.

When His Heart Stopped, a New Life Began (Links to an external site)

Sandeep S. Sodhi, MD, MBA

Nathan and Lynda Olsen loved to explore the southwestern Missouri countryside near their home in Carthage, so when they discovered a cozy coffeeshop situated on a picturesque bluff, they pulled in to savor the view and the java. But their relaxing afternoon quickly came to a jolting halt. 

Rheumatologist and Researcher Focuses on Lupus Care and Rural Health

Jessica Nicole Williams, MD, MPH

Dr. Jessica Williams, Assistant Professor of Medicine, WashU Medicine Division of Rheumatology, is a dedicated rheumatologist and clinical researcher with a deep commitment to advancing our understanding of lupus, an autoimmune disease of unknown cause that disproportionately affects women, racial and ethnic minorities, and individuals from lower socioeconomic backgrounds. Her work aims to uncover the […]

Connecting the dots (Links to an external site)

Graduate student Jiayu Ye works in the lab of Sheila A. Stewart, PhD. Stewart’s lab has identified a drug combination that makes T cells more effective in mice with metastatic breast cancer.

From detection to treatment, mapping a new future for breast cancer. WashU Medicine physicians at Siteman Cancer Center are recognized nationally for their expertise in leading-edge breast cancer therapies. Nearly 50 specialists in surgery, breast reconstruction, medical oncology and radiation oncology, radiology and pathology are part of the Breast Cancer Program at Siteman, providing personalized treatment plans […]

Global Studies Examine Hypertension Management and Barriers to Care (Links to an external site)

The ANDES study team after a meeting with the Ministry of Health in Lima, Peru. The WashU team: front row, first from left Dr. de las Fuentes; second from right Dr. Lindsay Underhill; back row Davila-Roman.

At WashU’s Global Health Center in the Institute for Public Health, teams of cardiologists, implementation scientists, and other experts are spearheading efforts to address one of the world’s most common and treatable risk factors for cardiovascular disease: hypertension. These efforts span multiple NIH/NHLBI-funded studies underway in Peru, Nigeria, India, and the United States.

Hospitalists Form Addiction Medicine Subcommittee to Tackle Patient Care Issues (Links to an external site)

From left to right: Benjamin Hoemann, MD, Thomas Hoyt, MD, Alex Lane, MD, Randy Laine, MD, Alyssa Moller, MD, and Corey Shy, MD

In 2023, several like-minded hospitalists noticed a gap in patient care, provider knowledge, and research within the division and hospital regarding the treatment of patients with addiction. These physicians—Benjamin Hoemann, MD; Thomas Hoyt, MD; Alex Lane, MD; Randy Laine, MD; Alyssa Moller, MD; and Corey Shy, MD—decided to come together to discuss these issues and […]

Hepatitis C ElimiNATION Awareness Tour (Links to an external site)

Dr. Nolan from Street Med STL with event coordinators, phelbotomists and staff from the Missouri Department of Medicaid during the Wellston Loop outreach event.

The Hepatitis C ElimiNATION Awareness Tour, sponsored by ABBVIE, brings Hepatitis C testing to underserved communities. The WashU Infectious Diseases Division’s Bridge to Health Program partnered with other state and community organizations including Street Med STL, the Missouri Department of Social Services, the Missouri Department of health and Senior Services, and Vivent Health to provide HIV […]

What Repeat COVID Infections Do to Your Body, According to Science (Links to an external site)

IKON Images/Adobe Stock

These days, it’s tempting to compare COVID-19 with the common cold or flu. It can similarly leave you with a nasty cough, fever, sore throat—the full works of respiratory symptoms. And it’s also become a part of the societal fabric, perhaps something you’ve resigned yourself to catching at least a few times in your life (even if […]

2024 Castle Connolly Top Doctors®

2024 Castle Connolly Top Doctors®

The Department of Medicine is proud to announce that 154 of our faculty have been selected for the 2024 Castle Connolly Top Doctors® list. The Top Doctors® selection process is entirely merit-based. Doctors cannot pay to be listed. These doctors are best-in-class healthcare providers, embodying excellence in clinical care as well as interpersonal skills. More […]

Bringing Healthcare to the Streets: The Mission of Street Med STL

Street Med-STL logo

In a world where healthcare often operates on rigid schedules and within traditional settings, there exists a growing need to adapt to the realities of those who cannot easily access or adhere to such structures. This is where organizations like Street Med STL step in, redefining healthcare delivery by taking it to the streets, quite […]

World Hypertension Day

theme of World Hypertension day observed on May 17 every year. also known as high blood pressure HBP.

May 17, 2024: “Measure Your Blood Pressure Accurately, Control It, Live Longer” The important World Hypertension Day was first held on 14 May 2005, and has since become an ever-expanding yearly event. This brief provides an update on high-impact hypertension-related research in Nigeria supported by Washington University. Hypertension, also known as raised blood pressure, affects […]