Study proposes novel drug to target arterial thrombosis

Researchers at the WashU Medicine  Sah Lab in the Center for Cardiovascular Research and their collaborators have published findings that provide a proof of concept for a  novel drug class to treat myocardial infarction and stroke. Rajan Sah, MD, PhD, a professor of medicine in the cardiovascular division, worked with multiple teams that collaborated to observe and describe a novel mechanoresponsive ion channel in platelets regulating platelet activation and arterial thrombosis, as well as novel small molecule drugs that target the pathway to prevent thrombosis.