News Achievements Announcements The DOM Insider Leadership/Appointments

Stephen Oh, MD – Samuel B. Grant Professor of Medicine

Stephen Oh, MD, PhD
Stephen Oh, MD, PhD, Professor

Colleagues, I am thrilled to announce that Dr. Stephen Oh has been named the Samuel B. Grant Professor of Medicine in the Department of Medicine.

Dr. Oh earned his undergraduate degree in Biochemical Sciences from Harvard University and his MD and PhD in Cancer Biology through the Medical Scientist Training Program at Northwestern University. After completing residency, fellowship, and postdoctoral training at Stanford University, he joined the WashU Medicine faculty in 2010. He is currently Co-Chief of the Division of Hematology and Professor of Medicine.

Dr. Oh is an internationally recognized physician-scientist whose research has advanced our understanding of blood cancers, particularly myeloproliferative neoplasms (MPNs). Over the past 16 years, he has led a highly successful translational research program investigating the molecular mechanisms that drive MPN development and progression. His pioneering studies identified dysregulated inflammatory signaling pathways as key drivers of disease and helped establish new therapeutic strategies that have been translated into clinical trials for patients. More recently, his laboratory has made important discoveries defining novel signaling dependencies in MPNs and acute myeloid leukemia, leading directly to innovative clinical studies and new opportunities for targeted therapies.

Dr. Oh’s scholarly accomplishments are exceptional. He has authored 100 peer-reviewed publications, along with numerous reviews, book chapters, and commentaries, with many appearing in leading journals including Nature Medicine, Nature Genetics, Nature Cancer, Nature Communications, New England Journal of Medicine, Blood, and the Journal of Clinical Investigation. His research has been continuously supported by the NIH for 15 years and has also received funding from organizations including the American Cancer Society, Damon Runyon Cancer Foundation, Doris Duke Foundation, Blood Cancer United, and the MPN Research Foundation. A recognized leader in hematology, Dr. Oh is frequently invited to present his work at national and international conferences and has received numerous honors, including the ASCO Young Investigator Award and the ASH Scholar Award. In 2025, he was elected to the American Society for Clinical Investigation in recognition of his scientific leadership and contributions to the field.

Dr. Oh is also a nationally recognized clinical expert in MPNs and has played a major role in advancing new therapies for patients. He has served as principal investigator on more than 30 multi-site clinical trials and contributed to multiple practice-changing studies that led to FDA approval of novel therapies for MPN patients. Equally important is Dr. Oh’s commitment to education, mentorship, and institutional leadership. He has mentored numerous graduate students, postdoctoral fellows, clinical fellows, and junior faculty, and currently serves as Program Director of a longstanding NHLBI-funded Molecular Hematology T32 training grant. His dedication to mentoring was recognized with the WashU Outstanding Faculty Award in 2025. As Co-Chief of Hematology, he has strengthened collaboration across the division, expanded research programs, and helped recruit and develop the next generation of faculty leaders.

Through his outstanding accomplishments as a researcher, clinician, educator, and leader, Dr. Oh has elevated the field of hematology and strengthened the research and clinical missions of WashU Medicine. The Samuel B. Grant Professorship recognizes these extraordinary achievements and supports his continued leadership and impact.

Please join me in congratulating Dr. Oh on this well-deserved honor.