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Epigenome’s role in cancer revealed in new study

Scientists at Washington University School of Medicine in St. Louis have analyzed the epigenomes of tumor cells across 11 cancer types and revealed important roles for this regulatory system of the genome in the way cancer forms, grows and spreads. (Image: Getty Images)
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Epigenetics of cancer critical in understanding tumor initiation, growth and spreading

For decades, scientists have been sequencing the DNA of many cancer types, identifying errors in the genetic code to help understand the formation of tumors, how they grow and what leads to their spreading. But sometimes cancer is driven by subtle changes in the way the genetic code is executed, rather than by mistakes in the code itself. This layer of regulation is called the epigenome.