The Mbalaviele lab and collaborators found that inflammasomes play a critical role in bone loss in mice caused by the chemotherapeutic drug, doxorubicin. This finding may inspire the development of a tailored adjuvant therapy that preserves the quality of this tissue in patients treated with this class of drugs.
Author: Julia
As bird flu spreads in the US, is it safe to eat eggs? What to know about the risk to humans (Links to an external site)
Avian influenza, aka bird flu, has spread to dairy cows in multiple states and one person in Texas. What to know about transmission, symptoms, and food risks.
The DOLF Project has Initiated a Clinical Trial of New Treatments for Onchocerciasis in Liberia (Links to an external site)
DOLF researchers announce initiation of a major a new clinical trial of treatments for onchocerciasis in Liberia. The study will compare the safety and efficacy of three new combination treatments with a reference treatment of albendazole plus ivermectin.
New sickle cell treatment center opens at BJC (Links to an external site)
ST. LOUIS – Barnes-Jewish Hospital is introducing the 12th sickle cell treatment center in the country. The center is revolutionizing healthcare for the underrepresented community affected by the disease.
Minority Health Month – Diversity Month (Links to an external site)
April celebrates both Diversity Month and National Minority Health Month, providing an opportunity to recognize and honor the diversity of the world around us while also addressing the disproportionate burden of premature death and illness in racial and ethnic minority groups.
Autism Acceptance – World Autism Awareness Day (Links to an external site)
Autism Acceptance Month takes place in April each year and is a time dedicated to promoting acceptance, understanding, and celebrating the diversity of people on the autism spectrum.
McNerney and Jasim discuss the long-term endocrine effects of cancer treatment (Links to an external site)
On October 10, 2023, Kyle P. McNerney, MD of the Department of Pediatrics at Washington University School of Medicine and Sina Jasim, MD of the Division of Endocrinology, Metabolism and Lipid Research, had their book chapter titled “Long-Term Effects of Cancer Treatment” published in Familial Endocrine Cancer Syndromes: Navigating the Transition of Care for Pediatric and Adolescent Patients.
How’s Your Soul? (Links to an external site)
Brother David, how’s your soul?” The question took me by surprise. It was time for my first advisement meeting with my residency program director. In medicine, the machine runs on competence and achievement of “milestones.” Yet, as I braced for a meeting to trudge through performance evaluations and in-training exam scores, I awoke to humanity.
Combining multiple meds into a single pill reduces cardiovascular deaths (Links to an external site)
‘Polypills’ recommended to reduce heart attacks, strokes but have been slow to gain favor
Some sarcoma patients improve with T cell immunotherapy (Links to an external site)
Strategy effective against some rare, aggressive sarcomas with no other treatment options A clinical trial led by researchers at Washington University School of Medicine in St. Louis has shown that a T cell immunotherapy — in which the patients’ own T cells are genetically modified to attack and kill cancer cells — is effective in […]
COVID Linked to Lower IQ, Poor Memory and Other Negative Impacts on Brain Health (Links to an external site)
“COVID-19 poses a serious risk to brain health, even in mild cases, and the effects are now being revealed at the population level,” clinical epidemiologist Ziyad Al-Aly said
Mahjoub Lab Celebrates Recent Publications on Critical Role of Centrosomes in Kidney Development and Function (Links to an external site)
Congratulations to the research team of the Mahjoub Laboratory, who are celebrating their multiple recent publications, one of which landed the cover of the journal JCI Insight.
Award of up to $31 million supports development of osteoarthritis treatment (Links to an external site)
Researchers aim to create treatment that promotes tissue regeneration, restores joints Osteoarthritis, a degenerative joint disease, limits the mobility of 32 million people nationwide, many to the point of significant disability. Affected individuals face limited options, as there are no drugs to cure or substantially lessen the disease, and invasive joint replacement is often the […]
Lasala Receives 2024 Miami Valves Lifetime Achievement Award (Links to an external site)
Dr. John Lasala, Professor of Medicine and Director, Structural Heart Disease in the Cardiovascular Division, was presented with the Lifetime Achievement Award at this year’s Miami Valves annual international structural cardiology conference hosted by the International Medicine Institute of the University of Miami Miller School of Medicine.
Husaini Featured During Men’s Health Segment on KSDK News (Links to an external site)
Dr. Mustafa Husaini, Assistant Professor of Medicine and Director of Sports Cardiology in the Cardiovascular Division, was recently featured in a segment on KSDK news for Heart Month. Today in St. Louis’ Rene Knott, Paul Cook and Anthony Slaughter spoke with Dr. Husaini about the importance of exercise in heart health, and specifically in men.
Civitelli Lab Published in JCI Insight (Links to an external site)
In a recent publication in JCI Insight, researchers from the Civitelli Lab unveil the pivotal role of connexin43 within mesenchymal lineage cells, shedding light on its influence in regulating body adiposity and energy metabolism in mice.
Scheller Lab and Colleagues Published in JCI Insight (Links to an external site)
Members of the Scheller Lab in collaboration with the Milbrandt and DiAntonio groups at WashU published a paper in JCI Insight in which they found that loss of Sarm1 could completely protect female mice against the development of bone loss and severe osteoblast suppression secondary to type 1 diabetes.
Phase 3 Trial of Breast Cancer Published in JAMA Oncology (Links to an external site)
Cynthia Ma , MD, PhD, lead author and Professor of Medicine in the Division of Oncology along with her colleagues Kiran Vij, Jeremy Hoog, Mark Watson and Erika Crouch in the Department of Pathology investigated the role of neoadjuvant anastrazole, fulvestrant or the combination in a multi-institutional trial.
Living Well: Pancreatic Cancer (Links to an external site)
ST. LOUIS, Mo. (First Alert 4) – About one in 64 people will get pancreatic cancer during their lifetime. It’s one of the more uncommon cancers, but it is one of the deadliest. In this Living Well, First Alert 4′s Taylor Holt talks with a doctor about why the disease is so deadly and what’s […]
Powers Carson and Arora discuss negative correlations between BMI and glycated albumin (Links to an external site)
In October of 2023, Jennifer Powers Carson, PhD and colleague, Jyoti Arora, MS of the Washington University School of Medicine, Center for Biostatistics and Data Science, had their work published by Clinical Biochemistry. The article was titled, “Glycated serum proteins and albumin but not glycated albumin show negative correlation with BMI in an overweight/obese, diabetic population from the United States.”
Center collaborator: “Connections ensure trust and sustainability” (Links to an external site)
If you hear a presentation by Professor of Medicine, Juliet Iwelunmor, PhD, from the Division of Infectious Disease at Washington University School of Medicine in St. Louis, you immediately sense that she is passionate, well spoken, driven and committed to work that drives impact. Since joining the Department of Medicine in September 2023, Iwelunmor—or “Dr. Juliet” […]
Zachary Crees, MD, on the Potential of Cell Therapy to Treat or Prevent Viral Infections After HSCT (Links to an external site)
The assistant clinical director of the Center for Gene and Cellular Immunotherapy at Washington University in St. Louis discussed Atara Biotherapeutics’ tabelecleucel and AlloVir’s posoleucel.
Dr. Safaa Hammoud Awarded AHA Postdoctoral Fellowship for Chronic Kidney Injury Research (Links to an external site)
Congratulations to Safaa Hammoud, PhD, a Postdoctoral Research Scholar in the laboratory of Leslie Gewin, MD, for receiving a 2024 American Heart Association (AHA) Postdoctoral Fellowship. The award provides two years of funding for her project “Blocking Tubular Cell Cycle Induces Protective Metabolic Changes in Chronic Kidney Disease.”
Transplant Nephrologist Anuja Java, Recent ICTS Grant Recipient, is Elected as Women in Nephrology Secretary (Links to an external site)
Congratulations to Washington University transplant nephrologist Anuja Java, MD, who was recently elected as Secretary of the Women in Nephrology (WIN) organization for 2024-2036. WIN, founded in 1983, promotes professional development, mentorship, and education for women and men in nephrology.
Deaf History Month 2024 (Links to an external site)
National Deaf History Month is celebrated March 13th to April 15th each year to commemorate the achievements of people who are deaf and hard of hearing.
Division of Oncology Receives Green Office Program Platinum Certification (Links to an external site)
The Division of Oncology was awarded the highest level of Green Office Certification from the WashU Office of Sustainability. Coordinated by the Office of Sustainability and endorsed by Resource Management, WashU’s Green Office Program aims to encourage offices across all WashU campuses to be champions of the university’s sustainability ethic.
AI may predict spread of lung cancer to brain (Links to an external site)
Method may inform personalized cancer treatments Physicians treating patients with early-stage lung cancer face a conundrum: choosing potentially helpful yet toxic therapies such as chemotherapy, radiation or immunotherapy to knock out the cancer and lessen the risk of it spreading to the brain, or waiting to see if lung surgery alone proves sufficient. When up […]
Happy Ramadan (Links to an external site)
Ramadan is the ninth month of the Islamic lunar calendar and holds great significance in the Islamic faith. It is observed by Muslims worldwide as a period of fasting, prayer, self-reflection, and increased devotion to Allah.
WashU Medicine rises to No. 2 in nation in NIH research funding (Links to an external site)
Ranking reflects success as thriving hub of scientific excellence, medical innovation In the realm of biomedical research, securing funding is a testament to an institution’s record of scientific accomplishments and potential for further advances to improve human health. In 2023, Washington University School of Medicine in St. Louis received the second-highest amount of funding from […]
Obituary: Philip E. Cryer, former director of endocrinology division, 84 (Links to an external site)
Philip E. Cryer, MD, a professor emeritus and former longtime director of the Division of Endocrinology, Metabolism & Lipid Research at Washington University School of Medicine in St. Louis, died Feb. 24, 2024, at a hospital in St. Louis following a heart attack. He was 84.
Dr. Mike Rich Receives BJH Neville Grant Award (Links to an external site)
Professor of Medicine, Associate Program Director for Cardiovascular Research andDirector of the Barnes-Jewish Hospital Cardiac Rapid Evaluation Unit Dr. Mike Rich has been selected for The Neville Grant Award, the highest clinical honor bestowed by BJH.
Mahmoud Appointed to ACC Reproductive Health & Cardio-Obstetrics Section Leadership Council (Links to an external site)
Dr. Zainab Mahmoud was recently appointed to a 3-year term on the leadership council of the Reproductive Health & Cardio-Obstetrics Section of the American Academy of Cardiology. Her term begins in April, 2024.
Institute staff changes set the stage for robust public health programs and initiatives (Links to an external site)
In service of Public Health at WashU, the Institute for Public Health announces the addition of new roles and a few staff promotions in several of its seven centers. The changes will help advance the Institute’s mission to harness the strengths of Washington University in St. Louis to address complex public health issues and disparities […]
Dr. David DeNardo Explores How the Tumor Microenvironment Affects Immune Responses to Cancer (Links to an external site)
David DeNardo, Ph.D., is a Professor of Medicine and Co-Director of the Tumor Immunology Program at the Washington University St. Louis, School of Medicine. His research team is working to understand why responses to cancer immunotherapy vary among patients. In studying and uncovering mechanisms of cancer immunology, Dr. DeNardo aims to identify strategies that can […]
Developmental Disabilities Awareness Month (Links to an external site)
Developmental Disabilities Awareness Month is an annual observance held in March to increase public awareness about developmental disabilities and promote inclusivity, acceptance, and understanding for individuals with these conditions.
Faculty Achievement Award nominations sought (Links to an external site)
Nominations are being accepted for Washington University in St. Louis’ annual Faculty Achievement Awards, known as the Arthur Holly Compton Faculty Achievement Award and the Carl and Gerty Cori Faculty Achievement Award.
Brain tumors: Fighting with targeted tools (Links to an external site)
Whether malignant or benign, a brain tumor is life-altering. Malignant tumors can spread and become deadly. And benign doesn’t mean harmless; benign tumors can cause serious problems such as paralysis, seizures and personality changes depending on which parts of the brain they affect.
DiPersio receives E. Donnall Thomas Prize (Links to an external site)
John F. DiPersio, MD, PhD, the Virginia E. and Sam J. Golman Professor of Medicine at Washington University School of Medicine in St. Louis, has received the E. Donnall Thomas Prize from the American Society for Transplantation and Cellular Therapy. Given annually, the E. Donnall Thomas Lecture and Prize recognize an eminent physician or scientist who has contributed […]
Women’s History Month (Links to an external site)
March offers us an opportunity to celebrate Women’s History Month This annual event honors women’s achievements and contributions throughout history. The theme for the 2024 Women’s History Month, “Women Who Advocate for Equity, Diversity, and Inclusion,” highlights the important role women play in promoting equality and diversity in their respective fields.
Dr. Atlee Baker, WashU Nephrology Fellow, Selected for ASN Internship (Links to an external site)
Atlee Baker, MD, MPH a first-year fellow at WashU Nephrology, has accepted an internship with the Transforming Dialysis Access Together (TDAT) initiative of the American Society of Nephrology (ASN).
Winn Awards Help Physicians Solve Healthcare Disparities (Links to an external site)
Dr. Thomas Odeny grew up in rural Kenya during the height of the HIV epidemic in sub-Saharan Africa. After graduating from medical school at the University of Nairobi, he decided to begin his career in HIV care as a way to give back to his community.
Washington University joins NIH cancer screening clinical trials network (Links to an external site)
New network to evaluate emerging technologies in diverse populations Washington University School of Medicine in St. Louis is joining a new clinical trials network launched by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), to investigate emerging technologies for cancer screening, with the goal of reducing cancer-related illnesses and deaths. […]
February is National Cancer Prevention Awareness Month (Links to an external site)
In the recent release of the American Cancer Society (ACS) new annual report, cancer death rates overall are falling but new cancer cases have picked up.
Black people have the highest rates of death from heart disease. Could more Black cardiologists help? (Links to an external site)
For Elston Harris, heart attacks seem to be a generational curse. Several men from his father’s side of the family — including Harris’ uncles — died from heart attacks. Harris, who is 59 and a former college basketball player, almost experienced a similar fate after his own heart attack in 2017. The only signs he was […]
New cell-based immunotherapy offered for melanoma (Links to an external site)
Siteman Cancer Center, based at Barnes-Jewish Hospital and the School of Medicine, is one of the first centers nationwide to offer a newly approved cell-based immunotherapy that targets melanoma.
Jacobi, Zickuhr named Loeb Teaching Fellows (Links to an external site)
Focus will be on mental health curriculum, improving skills for narrative feedback Celina Jacobi, MD, an instructor in child psychiatry, and Lisa Zickuhr, MD, an assistant professor of medicine, have been named the 2024-26 Carol B. and Jerome T. Loeb Teaching Fellows at Washington University School of Medicine in St. Louis.
University’s technology, innovation hub celebrates 100th faculty startup (Links to an external site)
Office of Technology Management fuels entrepreneurial spirit The first-floor walls at 4240 Duncan Ave. — home to Washington University in St. Louis’ Office of Technology Management (OTM) — are running out of room. And that’s a good thing. The logos of Washington University startup companies launched to shepherd promising university-owned diagnostics, therapeutics or other technologies to the […]
American Society for Clinical Investigation honors physician-scientists (Links to an external site)
Early-career scientists awarded for achievements in research Three early-career scientists at Washington University School of Medicine in St. Louis have been honored with the Young Physician-Scientist Award by the American Society for Clinical Investigation (ASCI). They are Tarin M. Bigley, MD, PhD; Jeffrey W. Brown MD, PhD; and Drew J. Schwartz, MD, PhD.
Ash Wednesday – First Day of Lent (Links to an external site)
Ash Wednesday marks the beginning of the Christian season of Lent. This day is marked by Mass, where ashes are placed on the foreheads of Christians in the shape of crosses by the priest.
Warm weather spurs on spring allergies (Links to an external site)
You may be cheering on the warm weather, but your sinuses are not. Rising temperatures mean trees are getting the cue to release pollen. Dr. Jennifer Monroy is a Washington University board-certified allergist and immunologist at Barnes-Jewish Hospital.