Mbalaviele Lab Published in eLife (Links to an external site)

Mbalaviele Lab Published in eLife

The Mbalaviele lab and collaborators found that inflammasomes play a critical role in bone loss in mice caused by the chemotherapeutic drug, doxorubicin. This finding may inspire the development of a tailored adjuvant therapy that preserves the quality of this tissue in patients treated with this class of drugs.

Minority Health Month – Diversity Month (Links to an external site)

Minority Health Month

April celebrates both Diversity Month and National Minority Health Month, providing an opportunity to recognize and honor the diversity of the world around us while also addressing the disproportionate burden of premature death and illness in racial and ethnic minority groups.

McNerney and Jasim discuss the long-term endocrine effects of cancer treatment  (Links to an external site)

Kyle P. McNerney, MD of the Department of Pediatrics at Washington University School of Medicine and Sina Jasim, MD of the Division of Endocrinology, Metabolism and Lipid Research

On October 10, 2023, Kyle P. McNerney, MD of the Department of Pediatrics at Washington University School of Medicine and Sina Jasim, MD of the Division of Endocrinology, Metabolism and Lipid Research, had their book chapter titled “Long-Term Effects of Cancer Treatment” published in Familial Endocrine Cancer Syndromes: Navigating the Transition of Care for Pediatric and Adolescent Patients.  

How’s Your Soul? (Links to an external site)

David Vermette, MD

Brother David, how’s your soul?” The question took me by surprise. It was time for my first advisement meeting with my residency program director. In medicine, the machine runs on competence and achievement of “milestones.” Yet, as I braced for a meeting to trudge through performance evaluations and in-training exam scores, I awoke to humanity.

Some sarcoma patients improve with T cell immunotherapy (Links to an external site)

According to a study led by Washington University School of Medicine in St. Louis, a new T cell immunotherapy — in which the patients’ own T cells are genetically modified to attack and kill cancer cells — is effective in treating some patients with two types of sarcoma, rare cancers of the body’s soft tissues. Shown is a cross section of a synovial sarcoma tumor.

Strategy effective against some rare, aggressive sarcomas with no other treatment options A clinical trial led by researchers at Washington University School of Medicine in St. Louis has shown that a T cell immunotherapy — in which the patients’ own T cells are genetically modified to attack and kill cancer cells — is effective in […]

Award of up to $31 million supports development of osteoarthritis treatment (Links to an external site)

Farshid Guilak, PhD, and Christine Pham, MD, collaborate on research together. They were photographed on March 13, 2024. MATT MILLER/WASHINGTON UNIVERSITY SCHOOL OF MEDICINE

Researchers aim to create treatment that promotes tissue regeneration, restores joints Osteoarthritis, a degenerative joint disease, limits the mobility of 32 million people nationwide, many to the point of significant disability. Affected individuals face limited options, as there are no drugs to cure or substantially lessen the disease, and invasive joint replacement is often the […]

Lasala Receives 2024 Miami Valves Lifetime Achievement Award (Links to an external site)

John Lasala, MD

Dr. John Lasala, Professor of Medicine and Director, Structural Heart Disease in the Cardiovascular Division, was presented with the Lifetime Achievement Award at this year’s Miami Valves annual international structural cardiology conference hosted by the International Medicine Institute of the University of Miami Miller School of Medicine.

Husaini Featured During Men’s Health Segment on KSDK News (Links to an external site)

Mustafa Husaini, MD

Dr. Mustafa Husaini, Assistant Professor of Medicine and Director of Sports Cardiology in the Cardiovascular Division, was recently featured in a segment on KSDK news for Heart Month. Today in St. Louis’ Rene Knott, Paul Cook and Anthony Slaughter spoke with Dr. Husaini about the importance of exercise in heart health, and specifically in men.

Civitelli Lab Published in JCI Insight (Links to an external site)

Roberto Civitelli, MD

In a recent publication in JCI Insight, researchers from the Civitelli Lab unveil the pivotal role of connexin43 within mesenchymal lineage cells, shedding light on its influence in regulating body adiposity and energy metabolism in mice.

Scheller Lab and Colleagues Published in JCI Insight (Links to an external site)

Erica Scheller, DDS, PhD

Members of the Scheller Lab in collaboration with the Milbrandt and DiAntonio groups at WashU published a paper in JCI Insight in which they found that loss of Sarm1 could completely protect female mice against the development of bone loss and severe osteoblast suppression secondary to type 1 diabetes. 

Living Well: Pancreatic Cancer (Links to an external site)

Channel 4 News Graphic

ST. LOUIS, Mo. (First Alert 4) – About one in 64 people will get pancreatic cancer during their lifetime. It’s one of the more uncommon cancers, but it is one of the deadliest. In this Living Well, First Alert 4′s Taylor Holt talks with a doctor about why the disease is so deadly and what’s […]

Powers Carson and Arora discuss negative correlations between BMI and glycated albumin  (Links to an external site)

Jennifer Powers Carson, PhD

In October of 2023, Jennifer Powers Carson, PhD and colleague, Jyoti Arora, MS of the Washington University School of Medicine, Center for Biostatistics and Data Science, had their work published by Clinical Biochemistry. The article was titled, “Glycated serum proteins and albumin but not glycated albumin show negative correlation with BMI in an overweight/obese, diabetic population from the United States.” 

Center collaborator: “Connections ensure trust and sustainability” (Links to an external site)

Juliet Iwelunmor, PhD

If you hear a presentation by Professor of Medicine, Juliet Iwelunmor, PhD, from the Division of Infectious Disease at Washington University School of Medicine in St. Louis, you immediately sense that she is passionate, well spoken, driven and committed to work that drives impact. Since joining the Department of Medicine in September 2023, Iwelunmor—or “Dr. Juliet” […]

AI may predict spread of lung cancer to brain (Links to an external site)

lung image

Method may inform personalized cancer treatments Physicians treating patients with early-stage lung cancer face a conundrum: choosing potentially helpful yet toxic therapies such as chemotherapy, radiation or immunotherapy to knock out the cancer and lessen the risk of it spreading to the brain, or waiting to see if lung surgery alone proves sufficient. When up […]

Happy Ramadan (Links to an external site)

Ramadan

Ramadan is the ninth month of the Islamic lunar calendar and holds great significance in the Islamic faith. It is observed by Muslims worldwide as a period of fasting, prayer, self-reflection, and increased devotion to Allah.

WashU Medicine rises to No. 2 in nation in NIH research funding (Links to an external site)

Washington University School of Medicine in St. Louis received in 2023 the second highest amount of funding from the National Institutes of Health (NIH) of all medical schools nationwide. This ranking reflects the school’s commitment to cutting-edge research and positions it as a key player in shaping the future of medicine. (Photo: Matt Miller/School of Medicine)

Ranking reflects success as thriving hub of scientific excellence, medical innovation In the realm of biomedical research, securing funding is a testament to an institution’s record of scientific accomplishments and potential for further advances to improve human health. In 2023, Washington University School of Medicine in St. Louis received the second-highest amount of funding from […]

Dr. David DeNardo Explores How the Tumor Microenvironment Affects Immune Responses to Cancer (Links to an external site)

David DeNardo, P.D

David DeNardo, Ph.D., is a Professor of Medicine and Co-Director of the Tumor Immunology Program at the Washington University St. Louis, School of Medicine.  His research team is working to understand why responses to cancer immunotherapy vary among patients. In studying and uncovering mechanisms of cancer immunology, Dr. DeNardo aims to identify strategies that can […]

Brain tumors: Fighting with targeted tools (Links to an external site)

Neurosurgeon Albert Kim, MD, PhD (center), and chief resident Adam Bevan, MD, PhD, perform a right parietal craniotomy to remove a brain tumor.

Whether malignant or benign, a brain tumor is life-altering. Malignant tumors can spread and become deadly. And benign doesn’t mean harmless; benign tumors can cause serious problems such as paralysis, seizures and personality changes depending on which parts of the brain they affect.

DiPersio receives E. Donnall Thomas Prize (Links to an external site)

John DiPersio, MD, PhD

John F. DiPersio, MD, PhD, the Virginia E. and Sam J. Golman Professor of Medicine at Washington University School of Medicine in St. Louis, has received the E. Donnall Thomas Prize from the American Society for Transplantation and Cellular Therapy. Given annually, the E. Donnall Thomas Lecture and Prize recognize an eminent physician or scientist who has contributed […]

Women’s History Month (Links to an external site)

Women's History Month

March offers us an opportunity to celebrate Women’s History Month This annual event honors women’s achievements and contributions throughout history. The theme for the 2024 Women’s History Month, “Women Who Advocate for Equity, Diversity, and Inclusion,” highlights the important role women play in promoting equality and diversity in their respective fields.

Washington University joins NIH cancer screening clinical trials network (Links to an external site)

Washington University School of Medicine in St. Louis is one of seven U.S. institutions joining a new national clinical trials network launched by the National Cancer Institute (NCI) to investigate emerging technologies for cancer screening, with the goal of reducing cancer-related illnesses and deaths. A key priority of the network is to ensure the clinical trials include participants from diverse populations. (Image: Getty Images)

New network to evaluate emerging technologies in diverse populations Washington University School of Medicine in St. Louis is joining a new clinical trials network launched by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), to investigate emerging technologies for cancer screening, with the goal of reducing cancer-related illnesses and deaths. […]

Black people have the highest rates of death from heart disease. Could more Black cardiologists help? (Links to an external site)

Around 60% of Black American adults have heart disease, and heart disease death rates are highest among Black Americans compared to other racial and ethnic groups, according to the American Heart Association.

For Elston Harris, heart attacks seem to be a generational curse. Several men from his father’s side of the family — including Harris’ uncles — died from heart attacks. Harris, who is 59 and a former college basketball player, almost experienced a similar fate after his own heart attack in 2017. The only signs he was […]

Jacobi, Zickuhr named Loeb Teaching Fellows (Links to an external site)

Lisa A. Zickuhr, MD

Focus will be on mental health curriculum, improving skills for narrative feedback Celina Jacobi, MD, an instructor in child psychiatry, and Lisa Zickuhr, MD, an assistant professor of medicine, have been named the 2024-26 Carol B. and Jerome T. Loeb Teaching Fellows at Washington University School of Medicine in St. Louis.

University’s technology, innovation hub celebrates 100th faculty startup (Links to an external site)

Patrick White, MD, PhD (left) and Randi Foraker, PhD

Office of Technology Management fuels entrepreneurial spirit The first-floor walls at 4240 Duncan Ave. — home to Washington University in St. Louis’ Office of Technology Management (OTM) — are running out of room. And that’s a good thing. The logos of Washington University startup companies launched to shepherd promising university-owned diagnostics, therapeutics or other technologies to the […]

Warm weather spurs on spring allergies (Links to an external site)

Jennifer Monroy, MD

You may be cheering on the warm weather, but your sinuses are not. Rising temperatures mean trees are getting the cue to release pollen.  Dr. Jennifer Monroy is a Washington University board-certified allergist and immunologist at Barnes-Jewish Hospital.