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A tribute to Stuart A. Kornfeld (1936–2025)

The Journal of Clinical Investigation •
David C. and Betty Farrell Professor of Medicine, Stuart A. Kornfeld, MD, assistant professor Wang-Sik Lee, PhD, and associate professor Balraj Doray, PhD, look over test results in the Clinical Sciences Research Building on April 10, 2019. MATT MILLER/WASHINGTON UNIVERSITY SCHOOL OF MEDICINE Half-century of research illuminates how cells work in health, disease - Kornfeld reflects on knowledge gained from longest running NCI grant - Stuart Kornfeld, MD, has led the field of glycobiology — the study of sugars bound to proteins — for decades, fueled by the same grant from the National Cancer Institute (NCI) that first supported his lab more than 50 years ago. He reflects on his career and the advances made possible by the NCI's longest running research grant.
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A giant in the field of biomedical research, Stuart Arthur Kornfeld, MD (Figure 1), passed away in St. Louis on Sunday, August 17, 2025, following complications from Parkinson’s disease. Stuart was the David C. and Betty Farrell Distinguished Professor Emeritus of Medicine at Washington University School of Medicine (WUSM). His leadership roles at WUSM, where he spent his entire clinical research career, included serving as co-director of the Division of Hematology-Oncology from 1976 to 1992 and codirector of the Division of Hematology from 1993 to 2009. Importantly, Stuart directed the Washington University Medical Scientist Training Program (MSTP) from 1991to 1997.