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$6.2 million to help develop gene therapy for HIV

The Source • June 4, 2024June 4, 2024

Researchers at Washington University School of Medicine in St. Louis have received a $6.2 million grant from the National Institutes of Health (NIH) to develop a gene therapy that would modify the immune system’s B cells to spur them to produce broadly neutralizing antibodies against HIV. In theory, such an approach could control or eliminate the infection without need for ongoing antiretroviral therapy. Shown is the engineered adenovirus designed to deliver HIV superantibody genes into B cells. (Image: Curiel Lab/School of Medicine)

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Genetically engineered B cells could produce super-antibodies to HIV