Dr. Osler Guzon joined the Department of Medicine in the Cardiovascular Division as an Assistant Professor in July 2025. He is a board-certified preventive cardiologist with clinical expertise caring for patients with cardiovascular-kidney-metabolic syndrome, pericardial diseases, and obesity-linked conditions such as diabetes and obstructive sleep apnea. Promoting nutrition and a healthy, active lifestyle as a foundation of care, Dr. Guzon takes a patient-centered approach aimed at improving the outcomes and overall well-being of his patients by integrating the latest research with early adoption of innovations and proactive management of the risk factors contributing to the development and progression of cardiovascular diseases.
Growing up, training, and practicing medicine in both urban and rural settings of Missouri—as well as living with his own predisposition for cardiometabolic disease—have shaped Dr. Guzon’s healthcare philosophy. He earned his combined bachelor’s and medical degrees from the University of Missouri-Kansas City School of Medicine’s accelerated six-year program before completing his Internal Medicine residency at Saint Louis University and his Cardiovascular Diseases fellowship at the University of Missouri-Columbia. After more than a decade of working within underserved communities outside metropolitan St. Louis, Dr. Guzon looks forward to collaborating with the world-class faculty at Washington University in St. Louis and bringing a heightened awareness of, empathy for, and deep commitment to those populations that often carry the heaviest burden of chronic illnesses.
Dr. Guzon embraces a holistic, value-based approach to patient care that centers on sustainable lifestyle modification complemented by medical therapies and procedures when appropriate. He believes that developing a nuanced understanding of each person’s unique determinants of health helps build a strong, trusting patient-doctor relationship and ensures that their care is rooted in dignity and respect. Beyond patient care, Dr. Guzon has held key leadership roles at those places in which he has worked, including Medical Staff President, Chairman of the Medical Executive Committee, and Chief of Utilization Review. During his training, he co-authored several peer-reviewed publications, and in recent years, he has shared his expertise nationally as a speaker on topics such as the intersection of cardiovascular disease with diabetes, obesity, and kidney disease, as well as the prevention of diabetes, heart failure, heart attack, stroke, and cardiovascular death.
Dr. Guzon is dedicated to providing compassionate, evidence-based, personalized medicine while helping to advance the university’s vision for excellence in clinical care, research, and education. He looks forward to mentoring the next generation of students and physicians-in-training within an environment that encourages integrity, humanity, and life-long learning from our patients, peers, and colleagues. His key interests are cardiovascular-kidney-metabolic syndrome, obesity-linked diseases, pericardial diseases, preventive medicine, general cardiology, PAD and heart failure.