Dr. Osama Altayar joined the Department of Medicine in the Division of Gastroenterology as an Instructor on July 1, 2019. He earned his medical degree from the Faculty of Medicine at Damascus University, Syria (2004-2011). After completing his medical education, he joined the Division of Preventive, Occupational and Aerospace Medicine at Mayo Clinic, Rochester, Minnesota where he initially worked as a research trainee then as a post-doctoral research fellow at the Mayo Clinic Evidence-Based Practice Research Program, previously known as the Knowledge Synthesis Program (2012-2013). Under the mentorship of Dr. Hassan Murad and Dr. Victor Montori, he led the work on multiple evidence reports for clinical practice guidelines for the American Urological Association, the Endocrine Society, the Society for Vascular Surgery, and the Undersea and Hyperbaric Medical Society. He also served as a methodology consultant on clinical guidelines committees. Subsequently, he went to Pittsburgh, Pennsylvania where he pursued his internal medicine internship and residency training at Allegheny General Hospital (2013-2016). During his internal medicine training, he developed a clinical interest in gastroenterology and hepatology and went to Washington University in St Louis for his gastroenterology fellowship training (2016-2019) after completing his residency. During his clinical training, he participated in numerous systematic reviews, meta-analyses, and evidence reports as a lead investigator and methodologist. He has also served as a trainee methodologist on the American Gastroenterological Association Clinical Guidelines Committee. Additionally, he participated in multiple data-based studies on the prediction of outcomes in gastrointestinal and liver diseases. His work has led to multiple manuscripts in peer-reviewed journals and he reviews for different journals including the Annals of Internal Medicine, Plos One, Digestive Diseases and Sciences, and Systematic Reviews. He continues to provide methodological consulting for systematic and technical reviews, and meta-analyses. His research interests are the use of big data, clinical research methodology, knowledge and guidelines synthesis, and evidence-based practice.