Dr. Karolyn Oetjen joined the Department of Medicine in the Division of Oncology as an Instructor on January 1, 2019.
Dr. Oetjen’s clinical interest is myelodysplastic syndromes and acute myeloid leukemia, with particular interest in therapy-related myeloid neoplasms and inherited predisposition to myeloid malignancies. The poor prognosis of relapsed, refractory and therapy-related myeloid neoplasms is an unmet clinical need for the development of novel therapeutics and cellular therapies. A primary focus of her research is applying single-cell genomic techniques to understand malignant clonal evolution within the bone marrow following chemotherapy treatment or hematopoietic stem cell transplantation, specifically in the setting of pre-existing mutations in DNA-damage repair genes.