BEGIN:VCALENDAR VERSION:2.0 PRODID:-//John T. Milliken Department of Medicine//NONSGML Events//EN CALSCALE:GREGORIAN X-ORIGINAL-URL:https://internalmedicine.wustl.edu/events/ X-WR-CALDESC:John T. Milliken Department of Medicine - Events BEGIN:VEVENT UID:20201014T1744Z-1602697440.4937-EO-18298-1@172.23.128.31 STATUS:CONFIRMED DTSTAMP:20261007T080521Z CREATED:20200928T185201Z LAST-MODIFIED:20200928T185201Z DTSTART;VALUE=DATE:20201201 DTEND;VALUE=DATE:20201203 SUMMARY: Asthma: New Discoveries and Therapies in the Age of COVID DESCRIPTION: *Program is subject to change Asthma and related diseases in t he form of COPD and asthma-COPD are a remarkably common\, affecting over 50 million patients in the US alone. Moreover\, this disease spectrum overlap s with inflammatory lung disease driven by respiratory viral infection\, in cluding COVID-19. In the case of asthma\, the pathology is thought to […] X-ALT-DESC;FMTTYPE=text/html:

*Program is subject to change

Asthma and related diseases in the form of COPD and asthma-COPD are a re markably common\, affecting over 50 million patients in the US alone. Moreo ver\, this disease spectrum overlaps with inflammatory lung disease driven by respiratory viral infection\, including COVID-19. In the case of asthma\ , the pathology is thought to arise from an aberrant type 2 immune response \, but the cellular and molecular mechanisms of this response require more precise definition\, including any contribution from non-type 2 immune mech anisms. Clinical trials based on these concepts have revealed both successe s and also some unforeseen failures that need to be addressed and included in the framework of respiratory viruses in general and SARS-CoV-2 in partic ular. This Keystone Symposia conference on asthma will highlight the most r ecent basic science breakthroughs in the pathogenesis of asthma and related inflammatory airway diseases and focus on the development of new therapeut ics for asthma and related progressive respiratory disease. In addition\, t he program will review these discoveries in the context of new therapeutic directions\, including the context of emerging information about COVID-19. The program has been designed to emphasize to identify\, validate\, and tra nslate new disease targets into new therapeutics. The topic is timely and u rgent given the recent mechanistic insights into inflammatory airway diseas e\, the current maturation of new biological therapies for this type of dis ease\, and the overlap of this information with progressive lung disease af ter respiratory viral infections\, including COVID-19.

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ORGANIZER;CN="McKinzie":MAILTO:tolliver.m@wustl.edu URL;VALUE=URI:https://internalmedicine.wustl.edu/events/event/asthma-new-di scoveries-and-therapies-in-the-age-of-covid/ ATTACH;FMTTYPE=image/jpeg:https://internalmedicine.wustl.edu/app/uploads/2020/09/Asthma-New-Discoveries-and-Therapies-in-the-Age-of-COVID-thumb.jpg END:VEVENT BEGIN:VTIMEZONE TZID:America/Chicago BEGIN:STANDARD TZOFFSETFROM:-0500 TZOFFSETTO:-0600 DTSTART:20201101T070000 TZNAME:CST END:STANDARD END:VTIMEZONE END:VCALENDAR