More than 6 million adults in the U.S. have heart failure, a condition that develops when the heart can’t pump enough blood to meet the demands of the body. While lifestyle changes and treatment can slow heart failure, there’s no cure. One reason is that heart failure and other heart conditions including heart attacks lead heart muscle to become thickened and scarred in a process known as fibrosis. Effective strategies to reverse or stop fibrosis in the heart or other organs after injury, as is needed for recovery, have remained elusive.
Discovery of Culprit Behind Scars in Heart Failure Points to Possible Treatment Target
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