News

Category: Research

The warrior within

MATT MILLER Robert D. Schreiber, PhD, right, consults with doctoral student Samuel O. Ameh. Their work exploring the immune system’s...

Outlook Magazine

Obese mouse mothers trigger heart problems in offspring

A diet high in fats and sugars is known for its unhealthy effects on the heart. Scientists now have found...

Washington University School of Medicine

Topical immunotherapy keeps skin cancer risk at bay

A combination of two topical creams already shown to clear precancerous skin lesions from sun-damaged skin also lowers the risk...

Washington University School of Medicine

$3.4 million aids effort to make a better flu vaccine

The influenza vaccine is only good for one flu season, partly because different strains of the virus circulate every year....

Washington University School of Medicine

Unnecessary testing for UTIs cut by nearly half

Tests to detect urinary tract infections (UTI) often are performed routinely in hospitals, even when patients don’t have symptoms. Such...

Washington University School of Medicine

New hope for stem cell approach to treating diabetes

Scientists working to develop more effective treatments for diabetes are turning to stem cells. Such cells can be transformed into...

Washington University School of Medicine

Medication for severe acne alters skin microbiome

Isotretinoin, a form of vitamin A, has been prescribed to treat acne for decades. It reduces oil production in the...

Washington University School of Medicine

Artificial intelligence and the future of medicine

Washington University researchers are working to develop artificial intelligence (AI) systems for health care, which have the potential to transform...

Washington University School of Medicine

Rates of chronic kidney disease, deaths outpace other diseases

Advances in treating cancer, heart disease and other major health conditions in recent decades have extended life spans for millions...

Washington University School of Medicine

Brain, muscle cells found lurking in kidney organoids grown in lab

Scientists hoping to develop better treatments for kidney disease have turned their attention to growing clusters of kidney cells in...

Washington University School of Medicine

Relapsed leukemia flies under immune system’s radar

Patients with acute myeloid leukemia (AML), an aggressive cancer of the blood, often are treated with stem cell transplantation, in...

Washington University School of Medicine

Viruses in blood lead to digestive problems

While studying viruses best known for infecting the brain, researchers at Washington University School of Medicine in St. Louis stumbled...

Washington University School of Medicine

Genetic testing helps predict disease recurrence in myelodysplastic syndrome

A DNA-based analysis of blood cells soon after a stem cell transplant can predict likelihood of disease recurrence in patients...

Washington University School of Medicine

New clues found to understanding relapse in breast cancer

A large genomic analysis has linked certain DNA mutations to a high risk of relapse in estrogen receptor positive breast...

Washington University School of Medicine

Analysis of prostate tumors reveals clues to cancer’s aggressiveness

Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic...

Washington University School of Medicine

Gene therapy method developed to target damaged kidney cells

Gene therapy has gained momentum in the past year, following the federal government’s approval of the first such treatments for...

Washington University School of Medicine

Air pollution contributes significantly to diabetes globally

New research links outdoor air pollution — even at levels deemed safe — to an increased risk of diabetes globally,...

Washington University School of Medicine

Chemotherapy-induced diarrhea traced to immune cells

Some 50 to 80 percent of cancer patients taking powerful chemotherapy drugs develop diarrhea, which can be severe and in...

Washington University School of Medicine

Decades of dedication lead to drug trial for rare, fatal illness

When Kim Morey was a young girl, a mysterious illness affected her family, striking relatives one by one at around...

Washington University School of Medicine

Scientists ID source of damaging inflammation after heart attack

Scientists have zeroed in on a culprit that spurs damaging inflammation in the heart following a heart attack. The guilty...

Washington University School of Medicine

Brain cancer vaccine effective in some patients

Most people with the deadly brain cancer glioblastoma die less than 18 months after diagnosis. But a multicenter clinical trial...

Washington University School of Medicine

15 Incredible Things That Happen to Your Body When You Lose Weight

Losing weight can seem like an overwhelming undertaking, but even dropping just a few pounds can have a big impact...

Reader's Digest

Eczema drug effective against severe asthma

Two new studies of patients with difficult-to-control asthma show that the eczema drug dupilumab alleviates asthma symptoms and improves patients’...

Washington University School of Medicine

Blood type affects severity of diarrhea caused by E. coli

A new study shows that a kind of E. coli most associated with “travelers’ diarrhea” and children in underdeveloped areas of the...

Washington University School of Medicine

Why chikungunya, other arthritis-causing viruses target joints

Chikungunya virus is a growing threat to the United States and other regions of the world as the mosquito that...

Washington University School of Medicine

The Belly Fat Battle

Visceral fat differs from subcutaneous fat in that it releases fatty acids and inflammatory substances directly into the liver rather...

Scientific American

How a light touch can spur severe itching

For some people, particularly those who are elderly, even a light touch of the skin or contact with clothing can...

Washington University School of Medicine

Best Practices for Physician-Scientist Training Programs: Recommendations from the Alliance for Academic Internal Medicine

AAIM

Experimental arthritis drug prevents stem cell transplant complication

An investigational drug in clinical trials for rheumatoid arthritis prevents a common, life-threatening side effect of stem cell transplants, new...

Washington University School of Medicine

Major milestone reached in effort to ID cancers’ genetic roots

Researchers nationwide have reached a major milestone in describing the genetic landscape of cancer. Scientists at Washington University School of...

Washington University School of Medicine

Drug compound shows promise against rheumatoid arthritis

Scientists have designed a new drug compound that dials down inflammation, suggesting possible future uses against autoimmune disorders such as...

Washington University School of Medicine

Antibiotic use increases risk of severe viral disease in mice

People infected with West Nile virus can show a wide range of disease. Some develop life-threatening brain infections. Others show...

Washington University School of Medicine

Infectious diseases docs may be lifesaving for patients with antibiotic-resistant infections

For patients with difficult-to-treat, drug-resistant infections, seeing an infectious diseases specialist can be a lifesaver. Such patients experienced significantly lower...

Washington University School of Medicine

The One Doctor You Need to See If You Get an Antibiotic-Resistant Infection

Patients who developed infections that were resistant to antibiotics were much more likely to survive if doctors specializing in infectious...

Consumer Reports

Infectious Diseases Consultation Reduces 30-Day and 1-Year All-Cause Mortality for Multidrug-Resistant Organism Infections

Abstract Background Multidrug-resistant organism (MDRO) infections are associated with high mortality and readmission rates. Infectious diseases (ID) consultation improves clinical...

Oxford Academic

No progress seen in reducing antibiotics among outpatients

Despite public health campaigns aimed at reducing unnecessary prescriptions for antibiotics, the drugs continue to be prescribed at startlingly high...

Washington University School of Medicine

Gut microbes influence severity of intestinal parasitic infections

A new study indicates that the kinds of microbes living in the gut influence the severity and recurrence of parasitic...

Washington University School of Medicine

CRISPR enhances cancer immunotherapy

Last year, the Food and Drug Administration approved the first cellular immunotherapies to treat cancer. These therapies involve collecting a...

Washington University School of Medicine

$5 million aids development of artificial red blood cells

Trauma is the leading cause of death for Americans under the age of 46. In the U.S., there are about...

Washington University School of Medicine

NCI director talks immunotherapy, cancer research on Med Campus

Norman E. “Ned” Sharpless, MD, the newly appointed director of the National Cancer Institute, visited the Medical Campus this week...

Washington University School of Medicine

Similarities found in cancer initiation in kidney, liver, stomach, pancreas

Recent research at Washington University School of Medicine in St. Louis demonstrated that mature cells in the stomach sometimes revert...

Washington University School of Medicine

Study of smoking and genetics illuminates complexities of blood pressure

Analyzing the genetics and smoking habits of more than half a million people has shed new light on the complexities...

Washington University School of Medicine

Cancer weapon

While Zika virus causes devastating damage to the brains of developing fetuses, it one day may be an effective treatment...

Washington University School of Medicine

Despite odds, fish species that bypasses sexual reproduction is thriving

The very rare animals that reproduce asexually — only about one in 1,000 of all living vertebrate species — are...

Washington University School of Medicine

ID’ing features of flu virus genome may help target surveillance for pandemic flu

The current influenza outbreak – the worst across the United States in nearly a decade – is worrisome but still...

Washington University School of Medicine

Light-triggered nanoparticles show promise against metastatic cancer

A new anti-cancer strategy wields light as a precision weapon. Unlike traditional light therapy — which is limited to the...

Washington University School of Medicine

Genetic lung disease’s molecular roots identified

Respiratory infections peak during the winter months, and most people recover within a few weeks. But for those with a...

Washington University School of Medicine

Memory loss from West Nile virus may be preventable

More than 10,000 people in the United States are living with memory loss and other persistent neurological problems that occur...

Washington University School of Medicine

Cancer Weapon: Zika virus kills glioblastoma stem cells in early research

Zika virus kills glioblastoma stem cells in early research BY TAMARA BHANDARI While Zika virus causes devastating damage to the...

Outlook Magazine

Study prompts new ideas on cancers’ origins

Rapidly dividing, yet aberrant stem cells are a major source of cancer. But a new study suggests that mature cells...

Washington University School of Medicine